Allergen specific immunotherapy
The underlying thought of treating an allergic dog by means of allergen-specific immuno-therapy (hypo-sensibilisation) is that the dog will gradually become less sensitive, or completely insensitive, to the allergens that cause the reaction. In order to achieve this, a therapy is compiled containing only the allergens that cause an allergic reaction in the dog.
Which dogs are eligible for Artuvetrin® Therapy?
In principle, dogs that have problems during at least three months of the year are eligible to undergo allergen-specific immunotherapy, such as Artuvetrin® Therapy. This treatment will help control the condition, and will significantly reduce the symptoms.
Advantages of immunotherapy from ArtuVet:
- Licensed therapy*
- Delivery within 10 working days
- Causal treatment
- Identical allergens for allery tests and therapies
- 1 vial of Artuvetrin® provides treatment for 10 months
- 1 vial, 1 concentration, ready to use
3 Willemse. Tijdschr. Diergeneesk. Deel 129 (2004) 402-408
4 Griffin, et. al. Vet. Immunol. Path 81 (2001) 363-383
5 Tarpataki, et. al. Hun. Vet. J. 126 (2004) 545-552
6 International Task Force on Canine Atopic Dermatitis. 2010 clinical practice guidelines for the treatment of canine atopic dermatitis. Vet Derm. 21 (2010): 301-308
* geregistreerd in Nederland.
Composition and characteristics
Depending on the findings of the Artuvetrin® Serum Test or the Artuvetrin® Skin Test, the preparations may be composed of 1 to 8 allergens or allergen mixes per vial. In order to obtain good quality for immuno-therapy, a certain concentration of allergens is required. In order to achieve this concentration, a maximum of 8 allergens are mixed within each vial of Artuvetrin® Therapy. Each Artuvetrin® Therapy is a magistral preparation based on the veterinary’s prescription, tailored specifically for treating a single individual patient. Each vial contains 10 ml.
Allergen-specific immuno-therapy has virtually no side-effects and long-term use is, therefore, no problem1.
A slight worsening of pruritus can be noted after the allergen injection. In sporadic cases anaphylactic shock can occur after injections with allergens with symptoms like lethargy, oedema of the head, pruritus, dyspnea, vomiting, diarrhoea or fainting. In such cases intravenous treatment with 1 to 5 milliliter (until effective, inject slowly) of an adrenaline solution (1:1000) is indicated.
The impact of a treatment can be assessed based on improvement in the clinical symptoms. Generally, the clinical symptoms start improving within a few months of starting the treatment.
1 Griffin CE and Hillier A – The ACVD task force on canine atopic dermatitis: allergen-specific immunotherapy. Veterinary Immunology and Immunopathology 81 (2001) 363-383.
Result of the treatment
The percentage of dogs responding favourably to treatment with Artuvetrin® Therapy amounts to approximately 75%1. It will take some time before the treatment results are shown. If no noticeable result has ensued eight to nine months after starting treatment, the advice is to stop treatment and re-examine the dog.
1 Willemse. Tijdschr. Diergeneesk. Deel 129 (2004) 402-408